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THE DAILY INDEX

Technology, AI, software, security, crypto and business

Across today’s newsletters

Today’s Index

ELON MUSK'S FULL OFFER LETTER TO BUY OPENAI REVEALS FIVE KEY DETAILS

Elon Musk's offer to buy OpenAI for $97.4 billion has a clear deadline: May 10. There is a stipulation that the buyers are able to examine OpenAI's financial and business records and interview OpenAI staff before the all-cash transaction is finalized. The offer undermines Musk's legal claims that OpenAI's startup's assets can't be transferred away for private gain. Musk will drop the bid to acquire OpenAI if the board commits to keeping it as a nonprofit.

BRAIN IMPLANT THAT COULD BOOST MOOD BY USING ULTRASOUND TO GO UNDER NHS TRIAL

The UK's Advanced Research and Intervention Agency (Aria) is funding a trial to test a brain-computer interface that directly alters brain activity using ultrasound to boost mood. The technology could revolutionize the treatment of conditions such as depression, addiction, OCD, and epilepsy by rebalancing disrupted patterns of brain activity. The device was developed by a US-based non-profit called Forest Neurotech. The trial will recruit patients who have had a part of their skull temporarily removed so that the device can be tested without having to perform surgery. It will run for three and a half years starting in March, and if successful, the device will move into full clinical trials.

AI-DESIGNED ENZYMES

One of the ultimate aims of protein design is to build entirely new enzymes from scratch. Scientists have traditionally discovered enzymes in nature and then adapted them through trial and error. New advances in AI may eventually lead to ways to create bespoke enzymes from the ground up, but doing so remains a formidable challenge. Many of the protein structural databases used to train models consist overwhelmingly of structures gleaned from 'frozen' images, preventing them from making accurate recreations of dynamic structures.

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