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THE OZEMPOCALYPSE IS NIGH

The FDA has declared that the shortage of GLP-1 drugs is over, meaning compounding pharmacies can no longer sell cheap GLP-1 drugs.

2025.03.17
astralcodexten.com8 min readTLDR

APPLE IS REPORTEDLY BRINGING LIVE TRANSLATION TO AIRPODS

Apple is planning to bring live translation to AirPods in iOS 19. The feature will allow users to hear a translated version of speech through their AirPods - their iPhones will play a translation from its speakers if the user responds. In addition to the feature, Apple plans to overhaul the design of iOS, iPadOS, and macOS this year. It will delay the release of its AI-upgraded Siri as it is taking longer than expected to deliver.

2025.03.14
theverge.com1 min readTLDR

NVIDIA'S NEXT CHIPS ARE NAMED AFTER VERA RUBIN, ASTRONOMER WHO DISCOVERED DARK MATTER

Most of Nvidia's most recent GPU architectures have been named after famous women scientists. Its next critical AI chip platform will be named after Vera Rubin, an American astronomer. Rubin discovered a lot of what is known about dark matter. Nvidia has been naming its architectures after scientists since 1998. It has never explained its naming convention and hasn't emphasized the diversity aspect of its choices, but its names are one of the most visible efforts in the tech industry to honor diversity.

2025.03.14
cnbc.com9 min readTLDR

ANTI-AGING ZEALOT BRYAN JOHNSON WANTS TO START ‘FOODOME SEQUENCING'

Bryan Johnson, the investor and founder behind the Don't Die movement, wants to start testing as much food as possible to hold brands accountable for unsafe food practices. One of the measures Johnson takes to extend his life is to eat healthy, but he says that eating healthy is not as easy as you'd think as it is hard to buy clean food. Most foods could contain toxins from various processing methods. Johnson plans to create a public database where people can donate money to have certain foods and brands tested for toxins.

2025.03.14
techcrunch.com3 min readTLDR

DWARF LEMURS COMBAT AGING DURING HIBERNATION BY REVERSING THEIR CELLULAR CLOCKS

The fat-tailed dwarf lemur, a hamster-sized primate from Madagascar, is the closest genetic relative to humans known to hibernate. They tend to live longer than expected given their size. New research shows that these small primates can reverse cellular aging. Telomeres in hibernating lemurs grow longer - the lengthening may serve as a protective mechanism against cell damage. Other mammals, including humans, have also exhibited telomere lengthening in response to extreme metabolic states. Understanding the mechanisms behind this phenomenon could pave the way for the development of novel treatments to slow or prevent age-related diseases.

2025.03.14
discovermagazine.com3 min readTLDR

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2025.03.14
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HTTP/3 IS EVERYWHERE BUT NOWHERE

HTTP/3 has been in development since at least 2016. While almost a third of web traffic has been migrated to it already, neither HTTP/3 nor QUIC (the protocol beneath it) are included in the standard libraries of any major languages. There are a rare few external libraries for some languages, but all are experimental and/or independent of other core networking APIs. Rollout of HTTP/3 has barely started rolling out to any popular open source tools. Underlying organizational differences are causing a split in technologies on the Internet. The technology is great, but it's a challenge if those benefits are not evenly distributed and only accessible to a small set of organizations and their customers.

2025.03.14
httptoolkit.com25 min readTLDR

BEWARE TECH CAREER ADVICE FROM OLD HEADS

People new to tech should take career advice from people who have been in the industry for more than a decade with enormous skepticism. The options available to people with established careers are dramatically different from what newcomers experience. These differences are so huge that newcomers and experienced workers might as well be in totally different industries. The tech industry of 15 or 20 years ago was very different from today.

2025.03.14
jacobian.org2 min readTLDR

GOOGLE GEMINI CAN NOW USE YOUR SEARCH HISTORY TO PROVIDE PERSONALIZED RESPONSES

Google Gemini 2.0 Flash Thinking model can now access users' search histories to provide more personalized information. It can only read search history for now, but Google plans to integrate the ability to connect with other Google apps and services. Gemini's access to search history is currently opt-in. Google says that search history will only be used when its reasoning model decides that it's helpful. The feature is now available to Gemini and Gemini Advanced subscribers on the web - it will be rolling out on mobile soon.

2025.03.14
macrumors.com1 min readTLDR

META IS LAUNCHING COMMUNITY NOTES IN THE US NEXT WEEK

Meta is releasing its version of Community Notes for its apps for users in the US on March 18. The program will copy a crowdsourced fact-checking system Twitter unveiled in 2021. Meta says it will focus on getting the feature right in the US before it rolls out to other countries. It may be hesitant to roll out the feature in the EU, where the European Commission is currently investigating X over the effectiveness of its version of Community Notes.

2025.03.14
techcrunch.com5 min readTLDR

CHOOSING LANGUAGES

People choose programming languages for projects based on a variety of reasons - there's no reason to be a jerk if you disagree with someone's language choice.

2025.03.14
steveklabnik.com6 min readTLDR

PUBLIC INTELLIGENCE

A public intelligence would make AI a global commons owned by everyone.

2025.03.14
kk.org9 min readTLDR

GOOGLE IS BRINGING LINUX TO ANDROID. HERE'S WHY THAT MATTERS

Google will soon allow users to run a full Linux environment that is officially supported and optimized directly on Android to give users more flexibility, deeper system control, and access to a more desktop-like Linux experience on mobile.

2025.03.14
spreadsheetpoint.com4 min readTLDR

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2025.03.13
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GOOGLE ANNOUNCES GEMINI ROBOTICS FOR BUILDING GENERAL PURPOSE ROBOTS

Gemini Robotics is a vision-language-action (VLA) model by Google DeepMind that aims to bring Gemini and AI to the physical world. It was created to make general purpose robots that can perform a wider range of real-world tasks than ever before. The VLA is built on Gemini 2.0 and has physical actions as an additional output modality for the purpose of directly controlling robots. Google built its robotic AI model to be able to understand and respond quickly to instructions or changes in the environment, capable of the kinds of things people can generally do with their hands and fingers, and adept with dealing with new objects, diverse instructions, and new environments. A video showing some of the model's capabilities is available in the article.

2025.03.13
9to5google.com2 min readTLDR

NEW INTEL CEO LIP-BU TAN WILL PICK UP WHERE PAT GELSINGER LEFT OFF

Lip-Bu Tan will become the CEO of Intel on March 18. Former CEO Pat Gelsinger was booted from the position on December 2 after several quarters of losses, rounds of layoffs, and canceled or spun-off side projects. Tan was previously on Intel's board from 2022 to 2024 and has been a board member for several other technology and chip manufacturing companies. Intel reported a loss of $18.76 billion in 2024, its first annual loss since 1986.

2025.03.13
arstechnica.com3 min readTLDR

LITHIUM-ION BATTERIES ARE REMAKING GOOGLE'S DATA CENTERS

Google installed 100 million lithium-ion cells across its data centers to provide backup power to its servers. The lithium-ion cells hold twice the power and take up half as much space as the lead-acid batteries they replaced, allowing the company to cut the number of cells required by three-quarters - more space for servers. Batteries are driving change in a myriad parts of the economy. Panasonic has shipped over 10 billion cells from its Nevada plant since it opened in 2015.

2025.03.13
techcrunch.com2 min readTLDR

GENERAL FUSION'S REACTOR PROTOTYPE CREATES PLASMA FOR THE FIRST TIME

Canadian startup General Fusion has created plasma inside its prototype reactor, a major milestone in proving its technology. The company uses technology that dates back to the 1970s - details are available in the article. The prototype is now forming plasmas daily - the next step is to compress the plasmas with a lithium liner to create fusion and heating from compression. The company hopes it will achieve scientific break-even equivalent by 2026.

2025.03.13
newatlas.com3 min readTLDR

I USE CURSOR DAILY - HERE'S HOW I AVOID THE GARBAGE PARTS

This post discusses how to make the Cursor experience as good as possible. It covers what to put inside the .cursorrules file, how to get the best output, and more. One of the biggest factors in a developer's experience with coding with AI is going to be what they are coding and which tech stack they are using. One of the best things about AI is that it can help developers tackle problems that would normally be outside of their reach.

2025.03.13
nickcraux.com4 min readTLDR

THE DUCKDB LOCAL UI

The DuckDB team and MotherDuck have released a local UI for DuckDB as part of the ui extension. The DuckDB UI uses interactive notebooks to define SQL scripts and show the results of queries. It can show databases, table summaries, notebooks, column insights, and more.

2025.03.13
duckdb.org5 min readTLDR

SOMETHING IS ROTTEN IN THE STATE OF CUPERTINO

It was clear when Apple announced Apple Intelligence that some of its features were more ambitious than others. Apple hinted strongly that the various features wouldn't all ship at the same time - the more trivial features would ship first. Its more ambitious features have been delayed until sometime 'in the coming year'. Apple appears to have pitched a story that wasn't true and set a course based on that.

2025.03.13
daringfireball.net23 min readTLDR

THE CULTURAL DIVIDE BETWEEN MATHEMATICS AND AI

The excitement around AI's potential contributions to mathematics doesn't always come with a nuanced understanding of what mathematics truly is and isn't. This post attempts to articulate these differences and hopefully build a bridge for better collaboration. Most mathematicians are not interested in AI creating new mathematics, but in processing and organizing existing knowledge. Even if AI was able to produce a proof of a major conjecture, it would fail to deliver the deeper understanding that mathematicians truly seek.

2025.03.13
links.tldrnewsletter.com25 min readTLDR

FILEPIZZA

FilePizza enables peer-to-peer file transfers inside the browser.

2025.03.13
github.comGitHub repositoryTLDR

NVIDIA WON THE AI TRAINING RACE, BUT INFERENCE IS STILL ANYONE'S GAME

Inference is a far more diverse workload compared to training - performance is predominantly determined by memory capacity, memory bandwidth, and compute - which of these is prioritized is heavily dependent on a model's architecture, parameter count, hosting location, and target audience.

2025.03.13
theregister.com5 min readTLDR

THE MOST FORBIDDEN TECHNIQUE

You should only train a model on outputs, not on an analysis of its outputs or on the technique used to analyze its outputs.

2025.03.13
links.tldrnewsletter.com30 min readTLDR

WHAT MATTERED IN GENAI IN 2024

The real value of generative AI will come from agents that can do things for users directly.

2025.03.13
weightythoughts.com16 min readTLDR

INSIDE GOOGLE'S INVESTMENT IN THE A.I. START-UP ANTHROPIC

Google owns 14% of Anthropic. Its investment gives it little control over the AI startup - Google holds no voting rights, no board seats, and no board observer rights at Anthropic. Google is set to invest an additional $750 million in Anthropic in September through a convertible debt - it has invested more than $3 billion into the AI company in total so far. It is only allowed to own up to 15% of Anthropic.

2025.03.12
nytimes.com4 min readTLDR

OPENAI SAYS IT HAS TRAINED AN AI THAT'S ‘REALLY GOOD' AT CREATIVE WRITING

OpenAI's CEO Sam Altman claims that his company has trained a new model that is 'really good' at creative writing. It is unknown how and when the model will be released. OpenAI has previously focused on challenges in the fields of math and programming rather than creative writing. The company experimenting with writing suggests that the latest generation of models has vastly improved on the wordsmithing front.

2025.03.12
techcrunch.com1 min readTLDR

NASA LAUNCHES NEW SPACE TELESCOPE AND SUITE OF SOLAR SATELLITES

SPHEREx and PUNCH lifted off from the Vandenburg Space Force Base at 11:11 PM ET on Tuesday. SPHEREx is a space telescope that will take images of the entire sky in more than a hundred colors that are invisible to the human eye. PUNCH is a suite of satellites that will study the Sun's outer atmosphere and solar wind. This article gets into the specifics of what the missions aim to do.

2025.03.12
nytimes.com7 min readTLDR

AUSTRALIAN MAN SURVIVES 100 DAYS WITH ARTIFICIAL HEART IN WORLD-FIRST SUCCESS

An Australian man lived with a totally artificial heart for 100 days before receiving a donor heart transplant in early March. The BiVACOR total artificial heart uses magnetic levitation technology to replicate the natural blood flow of a healthy heart. The implant is still in the early stages of clinical study, but it looks to be a promising alternative for patients who are unable to wait for a donor heart or when a donor heart is simply not available. There is still a long way to go before the artificial heart could be considered a replacement for a heart transplant - the functioning time span of the device is still significantly less than that of a donor heart.

2025.03.12
theguardian.com4 min readTLDR

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2025.03.12
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HERE'S HOW I USE LLMS TO HELP ME WRITE CODE

Using large language models (LLMs) to write code is difficult and unintuitive and there's little guidance to help people figure out how best to apply them. The patterns that work well do not come naturally to everyone. This post guides readers on how to achieve great results when programming with LLMs. One of the biggest advantages of LLMs is speed of development - LLMs enable developers to ship projects that they previously wouldn't have been able to justify spending any time on.

2025.03.12
simonwillison.net30 min readTLDR

OPENAI PUSHES AI AGENT CAPABILITIES WITH NEW DEVELOPER API

OpenAI's new Responses API is designed to help software developers create AI agents that perform tasks independently using the company's AI models. It will eventually replace the Assistants API, which OpenAI plans to retire in the first half of 2026. The Responses API can access the same models that power ChatGPT Search. The technology still has significant limitations, such as issues navigating websites and models making factual mistakes. OpenAI has also released the Agents SDK to provide developers tools to integrate models with internal systems, implement safeguards, and monitor agent activities.

2025.03.12
arstechnica.com3 min readTLDR

Y COMBINATOR FOUNDERS RAISING LESS MONEY SIGNALS A ‘VIBE SHIFT,' VC SAYS

There has been a 'vibe shift' from and of the founders in Y Combinator's current batch - people want to achieve their dreams with as little VC as possible. This wasn't due to a lack of interest by VCs - the round was oversubscribed. It's becoming more common for YC startups to raise less capital than was offered to them by investors. Raising less means founders maintain a larger ownership stake in their companies, giving themselves more ongoing business and exit options.

2025.03.12
techcrunch.com4 min readTLDR

THE CREATORS OF THE LAS VEGAS SPHERE WANT TO OPEN SMALLER MINI-SPHERES

Sphere Entertainment is working on a design for mini-Spheres with a capacity for about 5,000 people. Smaller investigations of the Sphere could potentially attract a wider range of artists. Designing and producing the custom video content required for the venue requires a hefty investment from performers. There are no details on where or when the mini-Spheres would be built. The company plans to build a second full-sized Sphere in Abu Dhabi.

2025.03.12
theverge.com3 min readTLDR

A 10X FASTER TYPESCRIPT

Microsoft is working on a native port of the TypeScript compiler and tools to drastically improve editor startup, reduce most build times, and substantially reduce memory usage.

2025.03.12
devblogs.microsoft.com5 min readTLDR

SIDEKICK

Sidekick lets Mac developers chat with local large language models about their files, folders, and websites without installing any other software.

2025.03.12
github.comGitHub repositoryTLDR