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Due to several factors, such as intellectual snobbery or regulatory barriers, the biopharma ecosystem is only set up for a limited number of disease areas, so a lot of important and commercially viable technologies are ignored.
AI excels at a lot of tasks that managers do, but there may be legal and other risks with using AI that might not be worth the cost savings.
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According to benchmarks, ARI beats OpenAI's Deep Research with a 76%
Put it to the test! You.com is giving TLDR readers their Team plan ($375 value), including:
Microsoft's NLWeb project enables websites to provide a conversational interface for users with a few lines of code, the AI model of their choice, and their own data. Sites using NLWeb can make their content discoverable and accessible to platforms that support MCP. NLWeb could play a similar role to HTML for the agentic web and allow users to interact directly with web content in a rich, semantic manner. The NLWeb project started with OpenAI, which was working on an early version last November.
Apple's iPhone 17 Air, which is expected to launch later this year, will weigh approximately 145 grams. The 6.6-inch, 5.5 mm-thin device will have a battery capacity of 2,800mAh and may use Apple's power-efficient C1 modem. There have been mixed reports regarding the iPhone 17 Air's potential battery performance, but Apple apparently determined that 60% to 70% of users will be able to use the device for a full day without needing to recharge throughout the day. The company is reportedly planning to release a battery case as an optional accessory to mitigate this problem.
Nvidia's NVLink Fusion, introduced at Computex this week, opens the NVLink interconnect tech to non-Nvidia-designed accelerators. NVLink enables multiple GPUs in a system or rack to behave like a single accelerator with shared compute and memory resources. The technology will be offered in two configurations: the first will be for connecting custom CPUs to Nvidia GPUs, and the second involves using NVLink to connect Grace and Vera CPUs to non-Nvidia accelerators. This should theoretically open up the possibility of superchip-style compute assemblies that feature any combination of CPUs and GPUs as long as Nvidia technology is involved.
23andMe will be sold to Regeneron Pharmaceuticals for $256 million. The sale includes 23andMe's Total Health and Research Services business and biobank of customer data and genetic samples. 23andMe says that customer data is anonymized and stored genetic samples are destroyed when users delete their accounts, but it is unclear how much information is retained. Regeneron's co-founder said that the purchase will further the company's large-scale genetics research into future drugs and treatments. 23andMe has collected genetic samples and data from more than 15 million customers.
At Fern, we're building open source tools to automatically generate idiomatic SDKs and documentation for any API.
Copilot coding agent lets developers delegate issues so they can focus on the creative, complex, and high-impact work that matters most. Developers simply assign issues to Copilot as they would another developer, and Copilot will work in the background using a secure cloud-based development environment. The agent will explore the repository, make changes, and validate its work before it pushes. Developers can ask Copilot to make changes to pull requests by leaving comments. The agent excels in low-to-medium complex tasks in well-tested codebases.
Anthropic's Claude Code SDK allows developers to programmatically integrate Claude Code into their applications. It enables running Claude Code as a subprocess. The SDK currently supports command-line usage. TypeScript and Python SDKs are coming soon. This page provides a guide on basic SDK usage.
Vibe coding represents a fundamental reimagining of the software development process. Instead of crafting lines of code, developers get to focus on vision and creative direction. It has the potential to transform technology development for the better - anyone with an idea for how technology could solve a problem can create that solution without specialized technical training. Vibe coding isn't just a technical shift, it's a cultural one that challenges assumptions about who gets to create technology and how that creation happens.
Apple is known for not giving its employees free lunches - even Steve Jobs paid for his own lunch. However, recently, the team working on Apple Intelligence were given vouchers to eat for free, breeding resentment among other teams. The team still shipped late. This article looks at the multiple failures within Apple's AI efforts. Apple may need to make some big changes to catch up, such as a big acquisition. While it doesn't usually make such moves, the current situation isn't typical - the company needs to let go of the past and operate in the future.
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The world's biggest event for AI builders is in SF from June 3-5. Speakers include leaders from OpenAI, DeepMind, Anthropic, and more, click here to get 30% off your ticket [18].
What began as a survival strategy against US sanctions has evolved into an initiative to position HarmonyOS as a dominant operating system across smartphones, tablets, TVs, and PCs.
This developer built custom terminal business cards to give others a way to connect to them that felt a little different.
This post looks at different ways to store information for large language models to access later in the interaction.
Poor design leads to semantic confusion and technical instability - this post presents a list of design principles to follow for formal database design.
Apple has been asked to approve Epic's submission for Fortnite on the US App Store or return to court to explain the legal basis as to why it has not done so.
A transcript of an interview with Microsoft's Chief Technology Officer, Kevin Scott, where he talks about the future of search, Microsoft's relationship with OpenAI, Scott's feelings about AI's capabilities scaling up over time, and his thoughts on AI as a creative tool.
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Manual testing on personal devices is TOO SLOW AND TOO LIMITED. It forces teams to CUT RELEASES A WEEK EARLY just to test before submitting them to app stores. And without broad device coverage, issues slip through.
While Apple has rolled out new AI features just like its competitors, they've mostly been notable for being delayed and underwhelming. The company announced Apple Intelligence last June, but some of the features are still being delayed - the new Siri won't be out in time for next month's WWDC, a year after it was first announced. Apple has devoted considerable resources to the technology and has little to show for it. While some attribute the struggles to decisions made by executives, others see symptoms of a deeper problem within the company.
OpenAI's Codex is an agentic coding tool that allows experienced developers to delegate rote and relatively simple programming tasks to an AI agent to generate production-ready code. It is a unique interface that can be accessed from the sidebar in the ChatGPT web app. Developers can include an 'AGENTS.md' file to give the agent custom instructions. Codex is built on a fine-tuned variation of OpenAI's o3 reasoning model. It is now rolling out to ChatGPT Pro, Enterprise, and Team users - Plus and Edu support will come at a later date.
The team at the US Department of Energy's National Ignition Facility has increased the yield of its net-positive fusion experiment to 8.6 megajoules. They made history in 2022 when they generated 3.15 megajoules in the first controlled fusion reaction to generate more energy than it consumed. While none of the experiments have been effective enough to feed electrons back to the grid, they show that controlled nuclear fusion is more than hypothetical.
A blood test has been approved by US health officials for diagnosing Alzheimer's in patients 55 and older who are showing early signs of the disease. The test identifies a key marker for Alzheimer's, beta-amyloid. The low costs and convenience of the blood test may help expand the use of drugs shown to slightly slow the progression of the disease. Previously, the only FDA-approved methods for detecting beta-amyloid were invasive tests of spinal fluid or expensive PET scans.
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Google's Director of AI Dr. Ali Arsanjani, and Datadog's VP of Engineering Sajid Mehmood, sat down to discuss the current and future states of AI, ML, and LLMs on Google Cloud. This guide distills the top 7 insights and actions for technical leaders [14], covering everything from upskilling teams to observability best practices. Read
Google's new ML Kit GenAI APIs, likely to be announced at I/O 2025, will enable developers to implement AI features like text summarization into their apps. The APIs will support image input and be available on a wide range of Android devices beyond the Pixel 9 series. They will enable on-device execution of AI foundation models like Gemini Nano to enhance app functionality, keeping user data private by processing data locally.
CSS' contrast-color() allows the browser to automatically assign contrasting color values. This can be handy, especially in large projects, as managing such small details can be a really hard task to get right. Developers just need to define one color. This post provides a guide on how to use contrast-color() and discusses accessibility considerations when using the function.
Google I/O is scheduled for May 20 to 21 at the Shoreline Amphitheater in Mountain View. The developer conference will showcase product announcements from across Google's portfolio, including Android, Chrome, Search, YouTube, and Gemini. It will likely reveal more about Android 16 and spotlight the capabilities in the latest versions of Android XR and Wear OS. Leaks over the past few weeks suggest that an updated Gemini Ultra model is on the way, which may indicate a pricier Gemini subscription.
Epic Games has received a request from Apple to unbundle its US and EU versions of Fortnite when submitting the game to the App Store. Apple says it will not consider adding the game to the US App Store until everything is fully settled involving litigation between Epic and Apple. Epic has asked the courts to force Apple to allow Fortnite to relaunch on the US App Store.
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The world's biggest event for AI builders is in SF from June 3-5. Speakers include leaders from OpenAI, DeepMind, Anthropic, and more, click here to get 30% off your ticket [20].
This repository contains the system prompts used for the Grok chat assistant and various product features across X and grok.com.
An encryption algorithm can be unbreakable, but systems are still vulnerable if key management isn't handled properly.
InventWood's Superwood is made from regular timber treated with food industry chemicals, which modifies the molecular structure of the wood, increasing the hydrogen bonds between cellulose molecules so that the resulting material has 50% more tensile strength than steel, with a strength-to-weight ratio that's 10 times better.
While large language models are okay at coding, they build jumbled messes when scaled.
Spaced repetition systems are programs that help build knowledge through flashcards.
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Despite significant investments in GenAI tooling, many engineering leaders still struggle to see the expected return on investment as developer adoption lags behind.
Apple's CarPlay Ultra is now available. Shipping initially in the Aston Martin, the next-generation interface expands the iPhone-based interface across multiple displays on the dashboard. It is able to display elements such as speed and fuel level. The new CarPlay Ultra requires an iPhone 12 or later running on iOS 18.4 or newer. A video that examines the new features of CarPlay Ultra is available in the article.
Coinbase customer data was recently stolen by cybercriminals using social engineering techniques. The incident may cost the company up to $400 million to fix. The data stolen includes names, addresses, phone numbers, emails, masked bank account numbers and identifiers, the last four digits of Social Security numbers, government ID images, and account balances. The attackers demanded a $20 million ransom, but Coinbase said it would not pay. It instead offered a $20 million reward fund for information leading to the arrest and conviction of the criminals responsible for the attack.
An infant in Philadelphia has been successfully treated with a customized CRISPR gene-editing therapy for a rare and deadly disease. The infant lacked an enzyme in his liver that normally converts ammonia to urea. This caused ammonia to build up and damage organs in the body. Before the treatment, the infant was in the eighth or ninth percentile for weight - after, he is now in the 35th to 40th percentile. The infant still needs medication, but now needs less. His treatment could potentially be used as a template for creating individualized treatments quickly for other patients with rare diseases.
Venus Aerospace has completed a short flight test of its rotating detonation rocket engine. The concept has been discussed academically for decades and has previously been tested in a handful of countries, but this is believed to be the first US-based flight test of the idea. The technology makes traversing the globe in under two hours possible. Venus still has a long way to go before it can provide highly efficient hypersonic commercial flight, but the flight test proves that such a future is at least possible.
Understanding the difference between complicated and complex problems is important because each requires a fundamentally different approach. Complicated problems are intricate but predictable, following structured, repeatable solutions, while complex problems are unique, requiring adaptive and often novel solutions. Recognizing whether a system is complicated or complex can help lead to solutions with more effective results. In many environments, systems are neither purely complicated nor purely complex - the key is learning to recognize when adaptability is needed and when structural solutions are enough.
Redis' decision to tighten license terms resulted in an exodus of contributors and the creation of Valkey. Valkey's creation resulted in a large number of pent-up requests for functionality being unleashed, some of which were being held up by Redis Open Source. The Valkey team will likely release v9 rather than 8.2 due to some changes that are a little bit more intrusive. It plans to be very conservative about what it puts into a version so that there are as few breaking changes as possible.
Meta's engineers are struggling to significantly improve the capabilities of the company's 'Behemoth' large language model. The model was intentionally slated for an April release, but this has now been delayed to fall or later. Staff are concerned that the model's performance won't match public statements about its capabilities. The company is contemplating significant management changes to its AI product group.
AI is rapidly commoditizing, and this is a good thing for Microsoft. CEO Satya Nadella believes that as AI becomes more accessible and its usage becomes more efficient, consumption will increase. The company has created its own AI architectures to prepare for this future. Microsoft's investment into AI projects will likely generate trillions of dollars in economic activity.