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HOW SAM ALTMAN PLAYED HOLLYWOOD

OpenAI made a series of calculated moves when it released Sora. The app initially had an opt-out clause for people's likenesses to be used in clips. This caused a flood of clips using copyrighted material to be created. The company then quickly pivoted to an opt-in model. This could cause legal trouble for OpenAI in the near future.

2025.10.20
hollywoodreporter.com11 min readTLDR

THE LITTLE-KNOWN CRYPTO POWERHOUSE BEHIND BILLIONS IN TRADING

Hyperliquid is a decentralized exchange with an automated trading pool and token buybacks. It is a booming platform for perpetual futures, the never-expiring contracts that dominate crypto speculation. Run by a team of roughly 15 people based in Singapore, the site's front end blocks US users, but anyone can trade on the blockchain that powers it. Hyperliquid was designed with transparency in mind - every trade, liquidation, and validator action is verifiable in real time, and Hyperliquid never takes custody of user funds. Much more about the two-year-old exchange is available in the article.

2025.10.20
links.tldrnewsletter.com11 min readTLDR

WHY THE NEXT GENERATION OF MRNA VACCINES IS SET TO BE EVEN BETTER

mRNA vaccines that code for virus-like nanoparticles produce a strong immune response while still being quick and cheap to make. Scientists at the University of Washington have shown that an mRNA version of a COVID-19 nanoparticle vaccine produces an immune response in mice that is up to 28 times higher than that of a standard mRNA vaccine. The more potent vaccine could lower side effects as patients receive lower doses. Scientists are already working on mRNA-launched nanoparticle vaccines for the flu, Epstein-Barr, and other viruses.

2025.10.20
newscientist.com3 min readTLDR

THE FIRST NON-OPIOID PAINKILLER

Post-operative pain relief has relied on opioids since ancient times. The FDA approved the first non-opioid pain reliever suitable for treating post-surgery pain in January. Vertex Pharmaceuticals' Journavx has known of the signs of the problematic side effects associated with opioids. While the drug likely won't serve as an outright opioid replacement, it is the first step on the journey to minimizing opioid usage.

2025.10.20
worksinprogress.co15 min readTLDR

Sponsored

[DATADOG EBOOK] 6 STEPS TO DIAGRAM YOUR CLOUD ARCHITECTURE

If you can't see how traffic moves, you can't truly calculate cost or detect latency issues — especially if you use dozens of services. In this eBook, Datadog & AWS Solutions Architects provide 6 steps to diagramming your cloud architecture [9] at the infra and traffic

2025.10.20
datadoghq.comSponsorTLDR

KNOWLEDGE CREATES TECHNICAL DEBT

Technical debt is essentially a pile of knowledge. Everything 'bad' about the code represents what has been learned about how to do software better. Fixing that code isn't a 'debt to pay off', but an investment opportunity that will reap rewards. Skipping the opportunity to fix code is wasting the investment previously made in learning, and this could lead to a loss in revenue as competitors make the most of their knowledge.

2025.10.20
lukeplant.me.uk3 min readTLDR

OPEN SOURCE IS THE MOST FRAGILE AND MOST RESILIENT ECOSYSTEM

Open source powers the internet. If it stopped being maintained by benevolent people, things would break. Companies fail, but open source is immortal. Open source will never fail to adapt to new markets because someone will force it to adapt either by contributing to it or forking it. Open source's fragility demands collective action to ensure its resilience.

2025.10.20
blog.peterzhu.ca16 min readTLDR

HOW TO SEQUENCE YOUR DNA FOR <$2K

The first human genome took $2.3 billion and 13 years to sequence. It now takes an Oxford Nanopore to sequence whatever DNA you want in less than 48 hours. The machine uses electrical nanopores to read the individual charge of each DNA base pair. It costs $1,000, making it possible to sequence your own DNA at home for around $1,100. Using the machine can help people avoid giving their DNA to companies and risking it being lost in a data breach.

2025.10.20
maxlangenkamp.substack.com5 min readTLDR

RESEARCH RESULTS ARE CULTURAL ARTIFACTS, NOT PUBLIC GOODS

Knowledge and scientific progress are very much private goods. It's all about specific people and how they think. Cultural artifacts can and will spread, but there's nothing free about it, and it won't spread equally everywhere. The view that scientific research is a public good is a naive and indefensible view.

2025.10.20
lemire.me2 min readTLDR

Sponsored

CRAVING MORE AI IN YOUR INBOX?

TLDR AI is your daily fix of LLMs, GenAI, and deep learning goodness. Same TLDR format. Still free.

2025.10.20
tldr.techSponsorTLDR

GENAI TRAFFIC SHARE UPDATE

ChatGPT continues to lose share, and Perplexity has exceeded a 2% threshold.

2025.10.20
threadreaderapp.com2 min readTLDR

Sponsored

Galaxy Trading connects institutions to digital asset markets with scale, speed, and sophistication. It offers everything institutions need to trade digital assets [4] efficiently.

2025.10.17
hubs.liSponsorTLDR

DOORDASH WILL USE WAYMO'S ROBOTAXIS FOR DELIVERY IN PHOENIX

DoorDash and Waymo have entered into a partnership that brings Waymo's driverless Jaguar SUVs into DoorDash's delivery fleet. Waymo will deliver orders from DoorDash's DashMart store starting in Phoenix. It plans to add more restaurants, retail, and grocery stores over time. Customers will have to go to the vehicle and unlock its trunk with the DoorDash app to retrieve their orders.

2025.10.17
theverge.com2 min readTLDR

HELION RECEIVES APPROVALS FOR NEXT PHASE OF CONSTRUCTION OF WORLD'S FIRST COMMERCIAL FUSION POWER PLANT

Helion has been granted a Conditional Use Permit to start the next phase of development for its commercial fusion power plant. This clears the way for the construction of the fusion generator building of the company's Orion fusion power plant in Malaga, Washington. Helion plans to deliver electrons to the grid before the end of this decade. The company's approach of rapid iteration and testing has enabled it to make steady progress toward a commercial fusion power plant. It was the first private fusion company to achieve 100 million degrees Celsius plasma temperatures, generally considered the required operating temperature for commercial fusion feasibility.

2025.10.17
helionenergy.com3 min readTLDR

CHINA OVERCOMES KEY BARRIERS TO UNLOCKING ALL-SOLID-STATE EV BATTERIES WITH 1,000 KM RANGE

Chinese scientists have achieved three breakthroughs that could be key to unlocking all-solid-state batteries. The first is iodine ions, which actively attract lithium ions in the interface between the electrode and the electrolyte, plugging the gaps and enabling a better bond. The second is a polymer material that can be bent 20,000 times and twisted into a twist without breaking. The third is a type of 'shield' on the electrolyte surface that passes needle penetration tests and can handle temperatures of over 120 degrees Celsius. The breakthroughs could result in a 100-kilogram battery pack that delivers over 1,000 kilometers of range.

2025.10.17
electrek.co4 min readTLDR

CLAUDE SKILLS ARE AWESOME, MAYBE A BIGGER DEAL THAN MCP

Claude Skills are folders that include instructions, scripts, and resources that Claude can load when needed to improve performance on specific tasks. Each skill has a Markdown file telling the model how to do something, optionally accompanied by extra documents and pre-written scripts the model can run to help it accomplish tasks. At the start of a session, Claude scans all available skill files and reads a short explanation for each one, which is very token-efficient. Skills are easy to share - the upcoming Cambrian explosion in Skills will make the MCP rush look pedestrian by comparison.

2025.10.17
simonwillison.net11 min readTLDR

HOW MUCH CAN TESLA PAY ELON MUSK? DELAWARE'S SUPREME COURT WILL DECIDE

The Delaware Supreme Court heard the latest set of arguments over Elon Musk's compensation package for Tesla on Wednesday. The pay package could hypothetically be worth well over $100 billion as of mid-October. A panel of justices will weigh whether the package was an extraordinary move that reflected undue influence or inadequately informed shareholders, or a properly conducted business decision. Meanwhile, Tesla's board of directors has proposed a new, future compensation package that could make Musk the world's first trillionaire if fully realized.

2025.10.17
npr.org11 min readTLDR

YOUTUBE JUST ATE TV. IT'S ONLY GETTING STARTED

YouTube has grown from a user-generated circus into the most powerful platform on Earth in two decades. The platform has become a dominant force in media, and there are signs the company is close to breaking through to the other hours people are spending on their TV sets. YouTube has paid out more than $100 billion to its creators, artists, and media partners over the past four years. Sports is in many ways the final frontier for YouTube to conquer.

2025.10.17
hollywoodreporter.com34 min readTLDR

YOU STILL NEED TO THINK

Agents don't remove the human job of setting goals, choosing constraints, and judging outputs.

2025.10.17
calv.info3 min readTLDR

Sponsored

CRAVING MORE AI IN YOUR INBOX?

TLDR AI is your daily fix of LLMs, GenAI, and deep learning goodness. Same TLDR format. Still free.

2025.10.17
tldr.techSponsorTLDR

DON'T WASTE YOUR 20S NOT TAKING BIG RISKS

Even if you fail, you'll have that experience, and if you do want to come back to it later, your learning ramp is going to be much shorter because you've already invested that time.

2025.10.17
blog.nateliason.com2 min readTLDR

Sponsored

❌ 💾 CUT KAFKA COSTS BY UP TO 80%

Your Kafka cluster is costing you - and often more than you think. Teams pay big-data prices for small-data streams, and burn engineering hours managing stateful brokers.

2025.10.16
aiven.ioSponsorTLDR

NEW APPLE M5 IS THE CENTERPIECE OF AN UPDATED 14-INCH MACBOOK PRO

Apple's new 14-inch MacBook Pro, iPad Pro, and Apple Vision Pro are the first devices to get the new M5 processor. The M5 features four high-performance CPU cores, six high-efficiency CPU cores, 10 GPU cores, and a 16-core Neural Engine. Its biggest upgrade is a leap in memory bandwidth that helps contribute to a 30% increase in GPU performance and a 45% increase in ray-traced GPU performance relative to the M4. The GPU includes a Neural Accelerator in each core that improves the performance of GPU-based AI workloads by up to 400%.

2025.10.16
arstechnica.com2 min readTLDR

GOOGLE'S AI CRACKS A NEW CANCER CODE

Google's latest biological AI system has generated and experimentally confirmed a new hypothesis for cancer treatment. It could lead to a promising new pathway for developing therapies to fight cancer. Cell2Sentence-Scale 27B (C2S-Scale) is a 27-billion-parameter foundation model for single-cell analysis built on Google's Gemma family of models. The discovery shows that scaling up biological AI models can result in them producing entirely new hypotheses.

2025.10.16
decrypt.co3 min readTLDR

INSIDE THE COLORADO FACTORY WHERE ATMOSZERO IS ELECTRIFYING STEAM

AtmosZero is building novel steam-producing heat pumps to replace the gas-burning boilers that factories rely on. Its Boiler 2.0 machine can be installed in a day in a process that is as simple as replacing an old gas boiler. While it isn't as efficient as other heat pumps, it is easier and cheaper to install, making it an attractive choice for factories that don't want to disrupt operations. AtmosZero aims to crank out 120 to 240 heat pumps per year by 2030.

2025.10.16
canarymedia.com6 min readTLDR

SPACEX OFFERS NEW LOOK AT V3 STARLINK SATELLITE FOR GIGABIT SPEEDS

Starlink V3 is significantly longer and larger than its predecessors. It uses a pair of longer solar arrays, and the central satellite bus is also bigger. The improvements will enable the satellites to deliver gigabit internet speeds. The larger size explains why SpaceX needs to use Starship to deploy V3 satellites rather than on a Falcon 9. Each V3 could weigh up to 2,000 kilograms.

2025.10.16
links.tldrnewsletter.com2 min readTLDR

Sponsored

ONE MAJOR REASON AI ADOPTION STALLS? TRAINING.

AI implementation goes sideways due to unclear goals and lack of skills. This AI Training Checklist [9] from You.com [9] pinpoints common pitfalls and guides you to build a capable, confident team that can make the most out of your AI investment. Set your AI initiatives

2025.10.16
about.you.comSponsorTLDR

ANNOUNCING VITE+

Vite+ is a unified toolchain for JavaScript. It works as a drop-in upgrade to Vite with additional features. Tooling complexity and performance have become real bottlenecks. Vite+ enables teams to focus on shipping products instead of wasting time evaluating, configuring, and debugging their tool stacks.

2025.10.16
voidzero.dev5 min readTLDR

DESIGNING APIS FOR VIBE CODING

Vibe coders discover APIs by asking their LLMs to solve a problem. This means apps looking to increase their vibe-ability will need to make it easier for LLMs to discover and correctly use their APIs. Flat and verbose beats concise, and conformity beats originality. This could mean there will be fewer innovative API designs in the future and that adoption might become tougher for newer programming languages.

2025.10.16
slinkydeveloper.com6 min readTLDR