TLDR

TLDR 2024-01-02

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01BIG TECH & STARTUPS

AMAZON'S SILENT SACKING

Many teams at Amazon have been in a hiring freeze for over a year and the employees that were left after the layoffs in 2023 are now leaving. The changes in the organization will likely result in a major AWS outage in 2024. There has already been an increase in large-scale events throughout Amazon. While Amazon is operationally strong, these operational practices depend on people, and when people are eliminated to increase stock prices, operational practices suffer.

justingarrison.com6 min read

02SCIENCE & FUTURISTIC TECHNOLOGY

THESE MOLECULAR JACKHAMMERS TAKE ON CANCER CELLS IN THE LAB, KILLS 99%

Scientists have discovered a way to combat cancer cells using vibrating molecules. The molecules vibrate synchronously to rupture the membranes of cancer cells. They are activated with near-infrared light, which allows for deeper penetration into the body than visible light. The technique demonstrated 99% efficacy in destroying cultured cancer cells in laboratory tests. When tested on mice models, half of the animals became cancer-free.

interestingengineering.com2 min read

WE ARE ABOUT TO ENTER THE GOLDEN AGE OF GENE THERAPY

The first CRISPR-based gene therapies were approved in the UK and the US late last year. While gene therapies promise to tackle both rare and common diseases, they will come with side effects like exorbitant prices, barriers to access, and ethical concerns. This article looks at how the field promises to bring better editing with more targets and equitable therapies for all in 2024 and beyond.

inverse.com11 min read

03PROGRAMMING, DESIGN & DATA SCIENCE

GITHUB MAKES COPILOT CHAT GENERALLY AVAILABLE, LETTING DEVS ASK QUESTIONS ABOUT CODE

GitHub is launching Copilot Chat in general availability for all users. It is free for verified teachers, students, and maintainers of certain open source projects and $10 per month for other users. Copilot Chat allows developers to ask for real time guidance with natural language. Powered by GPT-4, it is the most widely adopted AI developer tool in history. A list of Copilot competitors is available at the end of the article.

techcrunch.com3 min read

LARGE LANGUAGE MODEL COURSE

This course on large language models covers fundamental knowledge about mathematics, Python, and neural networks. It focuses on teaching students how to build and deploy the best possible LLMs using the latest techniques. The repository contains a list of notebooks and articles related to LLMs and resources for further learning.

github.comGitHub repository

04MISCELLANEOUS

STUFF WE FIGURED OUT ABOUT AI IN 2023

This article attempts to round up the highlights in AI development over 2023. It covers how to run LLMs on personal devices, fine-tuning models, the problem of gullibility, LLM applications, and more. LLMs can provide people who use them effectively with a significant boost to their quality of life. They're actually quite easy to build, but there's still a lot unknown about them and they're still unreliable for many applications. There are still many legal and ethical problems to overcome in the space.

simonwillison.net7 min read

A RECAP OF CONSUMER AI IN 2023

This thread provides a recap of AI products and trends that hit the mainstream in 2023. It goes through product launches month by month, providing user numbers and other relevant metrics. Highlights include ChatGPT reaching 100 million monthly active users in January, Balenciaga Pope going viral with 28 million views in March, AI covers taking off in June, users getting roasted by TikTok's AI memes in August, and X's Grok launching in December.

twitter.com6 min read