TLDR

TLDR 2023-01-20

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01GENERAL

02BIG TECH & STARTUPS

03SCIENCE & FUTURISTIC TECHNOLOGY

NEXT UP FOR CRISPR: GENE EDITING FOR THE MASSES?

Advances in CRISPR technology may soon make it possible for a vaccine that provides lifelong protection against heart disease. New forms of the technology, like prime editing, are broadening the scope of gene-editing treatments. They can be used to target diseases that aren't caused by rogue genes. An approach currently in testing to lower blood cholesterol could one day be used to protect people from high blood pressure and diabetes.

archive.ph6 min read

04PROGRAMMING, DESIGN & DATA SCIENCE

NEURAL NETWORKS: ZERO TO HERO

Neural Networks: Zero to Hero is a guide to building neural networks from scratch in code. It assumes readers have a solid programming background in Python and know intro-level math. The course covers backpropagation and training, implementing various models, diagnostic tools and visualizations, GPT, and more.

karpathy.aiTool

ODIGOS

Odigos is an observability control plane. It can generate distributed traces instantly for any application without code changes. Odigos can automatically detect programming languages and instrument them accordingly. It auto-scales collectors based on application usage, so there is no need to deploy or configure complex pipelines.

github.comGitHub repository

Sponsored

shortcut.comSponsor

05MISCELLANEOUS

THE ERA OF HAPPY TECH WORKERS IS OVER

The perks of working at a Silicon Valley firm are disappearing and unlikely to return. The current macroeconomic environment is forcing tech companies to optimize more for profit than growth. There were over 150,000 job cuts in 2022 and more are set for this year. The past few decades had managers fighting for talent, but now they are taking back control from employees. Despite this change, almost 80% of recently laid-off workers have been able to find employment within three months of being let go.

archive.ph7 min read