HARMFUL CHOLESTEROL LEVELS CUT IN HALF WITH ONE-TIME GENE EDITING DRUG IN EARLY TRIAL

Summary from the TLDR newsletter

A new experimental drug uses CRISPR to manipulate a single gene in the liver that normally boosts cholesterol levels. The approach works after one dose, helping people lower their levels of cholesterol and other fats in the blood permanently. While a Phase 1 clinical trial showed that the treatment is effective, its long-term safety is unknown. There are already safe and effective medications that can control cholesterol and fats, but patients tend to stop using them within a year due to side effects.