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Summary from the TLDR newsletter

Eli Lilly's weight loss pill, orforglipron, can help people reduce their body weight by as much as a fifth. The drug targets the same GLP-1 receptors as weight loss injections such as Mounjaro and Wegovy. While the weight loss seen in people taking the tablet is not as stark as that seen in those taking injectable forms of the drug, the tablet is significantly more accessible and convenient. Eli Lilly expects substantial demand when the new pill is launched.