PYX

Summary from the TLDR newsletter

pyx is an optimized backend for uv that makes uv even faster, more secure, and hardware-aware. It can be used to host private packages or as a frontend to public sources like PyPI. pyx solves many of the problems in uv that can't be solved with a client alone, but could be solved with a server. It is not yet generally available, but the development team is currently looking for more early users.