ONE DOSE OF EXPERIMENTAL DRUG NEARLY WIPES OUT STEALTHY CHOLESTEROL IN 'REMARKABLE' TRIAL

Summary from the TLDR newsletter

Lipoproteins are a type of cholesterol that is undetected by routine tests and undeterred by existing drugs, diet, or exercise. People with high levels of the cholesterol are at extremely high risk of cholesterol buildup in their arteries, which raises their odds of heart attack, stroke, and early death from cardiovascular problems. Eli Lilly has developed a drug called lepodisiran that dramatically reduced levels of lipoproteins for up to one year. The effects waned after a year but only slightly.