TLDR · MISCELLANEOUS

GENETICALLY EDITED MOSQUITOES HAVEN'T SCALED YET. WHY?

eryney.substack.com23 min read

Summary from the TLDR newsletter

Gene drives are a clever genetic trick that forces a particular gene to be inherited by nearly all offspring rather than the usual 50-50 chance in normal inheritance. They can propagate a desired mutation through an entire population theoretically with only a few mating events. Some iterations of gene drives have been demonstrated to work in fruit flies, but mosquitoes are much more complicated and we don't fully understand them yet. This technology is also being developed in countries where malaria is not endemic - the countries that have problems with mosquitoes may not want to deal with the potential ecological issues that may result from the use of gene drives.