SEMAGLUTIDE SO EFFECTIVE AT TREATING ARTHRITIS THAT PATIENTS WERE “MORE OR LESS WERE TREATED OUT OF THE STUDY”

Summary from the TLDR newsletter

A trial testing semaglutide on patients with knee osteoarthritis conducted in 11 countries found that the drug was so effective at treating the condition the participants no longer needed treatment by the end of the experiment. The study involved 400 obese patients who experienced pain when walking. The patients who received the drug lost weight, felt significantly less pain, and experienced more ease of everyday mobility compared to patients who received a placebo. Many of the improvements were due to taking weight off the affected knees, but the researchers think that semaglutide's anti-inflammatory effects also played a role.