A PRIMER ON THE CURRENT STATE OF LONGEVITY RESEARCH

Summary from the TLDR newsletter

This article takes a look at how far the field of aging research has progressed since 2021. Nothing particularly useful has come from sirtuin-focused therapies and this is unlikely to change. The increase in longevity-focused research institutions/grant programs/startups hasn't led to much progress, but it's still very early. Cellar reprogramming has shown promise in animal studies, but no therapies have reached clinical trials yet. There's still a lot we don't know about biological clocks - everyday consumers should probably avoid getting their biological age tested. While epigenetic clocks seem to be useful, their interpretation is a bit complicated.