‘SMART' ANTIBIOTIC CAN KILL DEADLY BACTERIA WHILE SPARING THE MICROBIOME

Summary from the TLDR newsletter

Gram-negative bacteria are often hardy, virulent, and quick to evolve resistance to antibiotics. Scientists have developed an antibiotic that kills pathogenic Gram-negative bacteria without impairing the gut microbiome. Still untested in humans, the compound's usefulness will depend on whether the bacteria will develop resistance to it in the long run. The time from an antibiotic's discovery to its approval for clinical use can be more than two decades, and there is not much money to be made with a novel antibiotic - around ten to twenty new Gram-negative antibiotics have been discovered in the past decade but none have gained approval from the US FDA.