DISRUPTING A SINGLE GENE COULD IMPROVE CAR T CELL IMMUNOTHERAPY, NEW STUDY SHOWS

Summary from the TLDR newsletter

CAR T cell therapy is a powerful type of immunotherapy that has begun to revolutionize cancer treatment. It involves engineering a patient's T cells so they recognize and attack cancer cells. New research has shown that disrupting a single gene in CAR T cells can make them more potent and able to fight tumors longer. The approach improved the therapy's effectiveness against multiple cancers in mice.